1. It is better to prevent waste formation than trying to clean up after their formation.
2. The synthetic methods should be designed for maximum incorporation into the final product of all the materials used in the process.
3. To the extent possible, synthetic methodologies should be designed for the use and generation of materials with low human and environmental toxicity.
4. Chemicals should be designed that preserving the effectiveness of its role, present a low toxicity.
5. Auxiliary substances (solvents, separation agents, etc..) Should be unnecessary as far as possible and should at least be safe.
6. Energy needs must be considered in relation to their environmental and economic impacts minimized. Synthetic methods should be carried to term temperature and pressure.
7. The starting materials should be renewable and not sinking in to the extent that this technically and economically practicable. 8. Unnecessary training products (blocking group, protection / deprotection, temporary modification of processes physical / chemical) should be avoided whenever possible.
9. Catalytic reagents (as selective as possible) are superior to stoichiometric.
10. The chemicals must be designed so that at the end of their function, not persist in the environment, but is fragmented into inert degradation products.
11. It must develop analytical methodologies that allow for real-time monitoring and control process prior to the formation of hazardous substances.
12. Substances and ways of its use in a chemical process should be chosen so that it is at least the possibility of accidents.
2. The synthetic methods should be designed for maximum incorporation into the final product of all the materials used in the process.
3. To the extent possible, synthetic methodologies should be designed for the use and generation of materials with low human and environmental toxicity.
4. Chemicals should be designed that preserving the effectiveness of its role, present a low toxicity.
5. Auxiliary substances (solvents, separation agents, etc..) Should be unnecessary as far as possible and should at least be safe.
6. Energy needs must be considered in relation to their environmental and economic impacts minimized. Synthetic methods should be carried to term temperature and pressure.
7. The starting materials should be renewable and not sinking in to the extent that this technically and economically practicable. 8. Unnecessary training products (blocking group, protection / deprotection, temporary modification of processes physical / chemical) should be avoided whenever possible.
9. Catalytic reagents (as selective as possible) are superior to stoichiometric.
10. The chemicals must be designed so that at the end of their function, not persist in the environment, but is fragmented into inert degradation products.
11. It must develop analytical methodologies that allow for real-time monitoring and control process prior to the formation of hazardous substances.
12. Substances and ways of its use in a chemical process should be chosen so that it is at least the possibility of accidents.
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